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Search Results for " bone morphogenetic protein 5 "

Targets Recommended: TGF-beta/Smad

2

抑制剂 & 化合物

1

天然产物

13

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T7799	BMP signaling agonist sb4 SB 4	TGF-beta/Smad	Stem Cells
	BMP signaling agonist sb4 (SB 4) 是苯并恶唑骨形态发生蛋白 4 (BMP4) 信号激动剂(EC50:74 nM)，能够稳定细胞内 p-SMAD-1/5/9 ，激活 BMP 信号。它还能激活典型 BMP 信号通路中的 BMP4 靶基因 (DNA 结合抑制剂，Id1和Id3)。
T83827	Adenosine-5'-O-(3-thiotriphosphate) sodium ATPγS,Adenosine 5'-(γ-thio)-triphosphate
	Adenosine-5'-O-(3-thiotriphosphate)（ATPγS）是一种purinergic P2Y11受体的激动剂。在表达人类或犬类P2Y11受体的CHO-K1细胞中，能够诱导肌醇磷酸累积（EC50s分别为1.2和19.3 µM）。ATPγS（10 µM）能抑制Junin病毒导致的编码骨形态生成蛋白6（BMP6）的mRNA水平增加，并减少Junin病毒感染的初代大鼠成骨细胞中的粒子形成单位（PFUs）。使用25 µM浓度时，可以诱导MIN6胰岛β细胞分泌胰岛素。

化合物

BMP signaling agonist sb4

Cat.No: T7799

Synonym: SB 4

Target: TGF-beta/Smad

Adenosine-5'-O-(3-thiotriphosphate) sodium

Cat.No: T83827

Synonym: ATPγS,Adenosine 5'-(γ-thio)-triphosphate

Cat. No.	Product Name	Target	Signaling Pathways
T3924	Astragaloside II 黄芪皂苷 II,Astrasieversianin VIII	TGF-beta/Smad	Stem Cells
	Astragaloside II (Astrasieversianin VIII) 是一种分离自黄芪中的天然化合物。

天然产物

Astragaloside II

Cat.No: T3924

Synonym: 黄芪皂苷 II,Astrasieversianin VIII

Target: TGF-beta/Smad

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00681	BMP-5 Protein, Human, Recombinant (hFc) bone morphogenetic protein 5<...	Human	HEK293 Cells
	Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily. In agreement with a possible role in the control of cell death, BMP-5 exhibited a regulated pattern of expression in the interdigital tissue. Transcripts of BMP-5 and BMP-5 protein were abundant within the cytoplasm of the fragmenting apoptotic interdigital cells in a way sugges...
TMPY-01764	BMPR1A/ALK-3 Protein, Human, Recombinant (His) bone morphogenetic protein recept...	Human	HEK293 Cells
	BMPR1A/ALK-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is P36894.
TMPJ-00966	GDF-5 Protein, Human, Recombinant Lipopolysaccharide-associated protein 4,Cartilage-d...	Human	E. coli
	Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor protein consisting of a 354 amino acid (aa) Nterminal proregion and a 120 aa C-terminal mature peptide. Mature human GDF-5 shares 99% aa sequence identity with both mature mouse and rat GDF-5. GDF-5 signaling is mediated by formation of a heterodimeric complex consisting of a ty...
TMPY-05485	BMPR1A/ALK-3 Protein, Human, Recombinant (hFc) ACVRLK3,SKR5,10q23del,CD292,bone morph...	Human	HEK293 Cells
	BMPR1A/ALK-3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number is P36894.
TMPJ-00325	BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His) BMP Type-1A Receptor,Bone Morphogenetic	Human	HEK293 Cells
	Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, ...
TMPY-05308	CD45 Protein, Human, Recombinant (aa 1-529, His) GP180,B220,L-CA,protein tyrosine phosphatase, recep...	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-05387	SLAMF7 Protein, Human, Recombinant (hFc) SLAM family member 7,19A,SLAM7,CS1,CD319,CRACC	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc) GLUR6,EAA4,MRT6,GLR6,glutamate receptor, ionotropic, kainate...	Human	HEK293 Cells
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the gl...
TMPY-05547	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated CS1,SLAM7,CD319,SLAM family member 7,CRACC,19A	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPJ-00854	ETS1 Protein, Human, Recombinant (His) V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian),...	Human	E. coli
	ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death As...
TMPY-05498	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) HDLQTL6,SR-BI,SRB1,CD36L1,CLA-1,CLA1,scavenger receptor clas...	Human	HEK293 Cells
	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPK-01357	SIRP alpha V5 Protein, Human, Recombinant (His & Avi) MFR,PTPNS1,P84,BIT,MYD-1,MYD1,SHPS-1,SIRPA,SIRP α,SIRP α V	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.
TMPK-01363	SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated SIRP alpha,MFR,PTPNS1,SIRP α V5,P84,SHPS-1,BIT,CD17...	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...

重组蛋白

BMP-5 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00681

Species: Human

Expression System: HEK293 Cells

BMPR1A/ALK-3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01764

Species: Human

Expression System: HEK293 Cells

GDF-5 Protein, Human, Recombinant

Cat.No: TMPJ-00966

Species: Human

Expression System: E. coli

BMPR1A/ALK-3 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05485

Species: Human

Expression System: HEK293 Cells

BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00325

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Human, Recombinant (aa 1-529, His)

Cat.No: TMPY-05308

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05387

Species: Human

Expression System: HEK293 Cells

GRIK2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04318

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05547

Species: Human

Expression System: HEK293 Cells

ETS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00854

Species: Human

Expression System: E. coli

SR-BI/SCARB1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05498

Species: Human

Expression System: HEK293 Cells

SIRP alpha V5 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01357

Species: Human

Expression System: HEK293 Cells

SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01363

Species: Human

Expression System: HEK293 Cells

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